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Advice for Scabies

Scabies is a contagious skin condition caused by infestation with the microscopic mite *Sarcoptes scabiei*. The female mite burrows into the upper layer of the skin to lay eggs, which triggers an intense allergic reaction and severe itching.

Scabies spreads easily through close skin-to-skin contact, making it common in households, nursing homes, and crowded living conditions. It can also spread through contact with contaminated clothing, bedding, or towels, although this is less common.

The main symptom of scabies is **intense itching**, which often worsens at night. A rash usually develops, characterized by small red bumps, blisters, or pimple-like lesions. Common sites for the rash include the webbing between the fingers, wrists, elbows, armpits, waist, buttocks, and genital area.

Diagnosis is primarily clinical, based on the appearance of the rash and itching pattern. Sometimes, skin scrapings may be examined under a microscope to confirm the presence of mites, eggs, or fecal matter.

Treatment involves the use of **prescription topical scabicides**, such as permethrin cream or malathion lotion, applied over the entire body from the neck down and left on for a specified time before washing off. In some cases, oral ivermectin may be prescribed, especially for widespread or difficult-to-treat infestations.

All household members and close contacts should be treated simultaneously to prevent reinfestation. Bedding, clothing, and towels used in the days before treatment should be washed in hot water or sealed in plastic bags for several days to kill any mites.

With proper treatment, symptoms usually improve within a few days, but itching may persist for several weeks due to the ongoing allergic response. If symptoms continue or worsen, a follow-up with a healthcare provider is recommended.

The primary symptom of scabies is intense itching, which usually worsens at night. This itching results from an allergic reaction to the mites, their eggs, and their waste products.

Shortly after infestation, a rash develops, often consisting of small red bumps, blisters, or pimple-like lesions. The rash can appear anywhere on the body but is most commonly found in certain characteristic locations.

Typical sites affected include the spaces between the fingers, wrists, elbows, armpits, waist, buttocks, genital area, and around the nipples. In infants and young children, the head, face, neck, palms, and soles may also be involved.

Another distinctive symptom is the presence of tiny, thread-like burrows visible on the skin. These burrows represent tunnels made by the female mites as they burrow under the skin to lay eggs. Burrows appear as thin, irregular, raised lines and are often difficult to see.

Scratching due to itching can lead to skin damage, secondary bacterial infections, and thickening or scaling of the skin in chronic cases.

In some individuals, especially those with weakened immune systems, a severe form called **crusted scabies** can develop. This form causes thick crusts of skin containing large numbers of mites and is highly contagious.

Symptoms typically begin 2 to 6 weeks after the initial exposure, but in people who have had scabies before, itching can start within 1 to 4 days.


Scabies is caused by infestation with the microscopic mite *Sarcoptes scabiei* var. hominis. The female mite burrows into the upper layer of human skin to lay eggs, which leads to an allergic skin reaction.

The condition is highly contagious and spreads primarily through prolonged, direct skin-to-skin contact with an infected person. This includes close physical contact such as hugging, shaking hands, or sexual activity.

Scabies can also spread, though less commonly, by sharing clothing, bedding, or towels that have been recently used by an infested person, as mites can survive for 24 to 36 hours away from the human body.

Infestation is more common in crowded living conditions, nursing homes, hospitals, and childcare centers where close contact between individuals is frequent.

Anyone can get scabies, regardless of age, sex, or hygiene, but the risk is higher in people living in close quarters or with limited access to healthcare.


Permethrin 5% cream is the first-line treatment for scabies in the UK. Patients should apply the cream to the entire body from the neck down, making sure to cover all skin folds, between the fingers and toes, and under the nails. For young children and infants, the face and scalp should also be treated. The cream should be left on the skin for 8 to 14 hours, usually overnight, before being washed off. A second application is recommended seven days later to kill any mites that may have hatched after the first treatment. Permethrin is generally well tolerated, though some people may experience mild skin irritation.

Oral ivermectin is used when topical treatments are unsuitable, for example, in cases of crusted scabies, treatment failure, or outbreaks in institutions. The usual dose is 200 micrograms per kilogram of body weight, given as a single dose, with a second dose given 7 to 14 days later. It should not be given to children weighing less than 15 kilograms, pregnant or breastfeeding women, or individuals with certain neurological conditions. Side effects are uncommon but may include headache, dizziness, nausea, or mild skin rash.

All household members and close contacts should be treated at the same time to prevent reinfestation. Bedding, clothing, and towels used within the previous few days should be washed in hot water or sealed in plastic bags for at least 72 hours to kill any mites. It is common for itching to continue for two to four weeks after treatment because of the allergic reaction to dead mites; this does not mean the treatment has failed. If symptoms persist beyond this time or worsen, patients should seek further medical advice.


If permethrin or ivermectin cannot be used or are not effective, alternative treatments for scabies are available. One commonly used alternative topical treatment is **malathion 0.5% aqueous lotion**, which is applied to the entire body from the neck down and left on for 24 hours before washing off. Malathion kills the mites and their eggs, but it has a strong odor and can cause skin irritation in some people.

Another option is **benzyl benzoate 25% lotion**, which is also applied to the whole body below the neck and left on for 24 hours. Benzyl benzoate may cause stinging and irritation, so care should be taken when using it, especially in children.

For crusted scabies or severe infestations, combinations of topical treatments with oral ivermectin may be necessary to fully eradicate the mites.

In cases where topical insecticides are unsuitable, or for patients who experience adverse reactions, supportive care such as soothing lotions, antihistamines for itching, and management of secondary bacterial infections may be used.

It is important that all close contacts are treated simultaneously and that clothing, bedding, and towels are cleaned appropriately to prevent reinfestation.


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